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Фармацевтические ферментеры

Pharmaceutical fermenters

System Overview and Scalability

These fermenters are engineered for precise operation with cell cultures and microorganisms. The product line starts at a working volume of 10 liters and scales up to 10,000 liters. Developed with cutting-edge technology and design trends, these units allow for the configuration of both classical and hybrid process systems.

Design and Control Features

The equipment features an ergonomic design mounted on a single base frame (skid-mounted). Key operational parameters include:

  • Temperature Control Range: From -20°C to 130°C.

  • Sterilization Temperature: Up to 130°C.

  • Automation: Managed by an industrial-grade microprocessor with validated software.

  • Process Monitoring: Detailed continuous monitoring via a comprehensive sensor array.

  • Lid Handling: A hydraulic lifting device is available for vessel volumes up to 1,000 liters.

  • Aeration and Filtration: Equipped with a deep aeration system and advanced filtration for process air and feed gases.

Technical Specifications and Configuration

The fermenter configuration includes all essential components for reliable and user-friendly operation with microorganisms or cell cultures:

  • Vessel Construction: Fabricated from AISI 316L stainless steel.

  • Thermostatic Station: Ensures temperature maintenance uniformity within 0.1°C.

  • Cleaning and Sterilization: Integrated CIP (Clean-in-Place) and SIP (Steam-in-Place) stations.

  • User Interface: Intuitive touchscreen control panel.

  • Agitation System: Bottom-entry mixer with a magnetic drive to ensure hermetic integrity.

  • Sampling: Aseptic, sterilizable sampling valves.

  • Auxiliary Connections: Dedicated ports for peristaltic pump integration.

  • Measurement Systems: Strain gauge (load cell) system for precise control of weight, volume, or level.