Equipment for obtaining soft dosage forms

The production of semisolid dosage forms—such as ointments, creams, gels, and pastes—demands a rigorous technological approach to ensure product sterility, uniform component distribution, and long-term emulsion stability. INEX provides a complete spectrum of equipment, ranging from laboratory-scale mixers for R&D to fully automated industrial lines, customized to meet the specific viscosity and rheological requirements of your formulation.

Our systems focus on achieving a perfect homogeneous structure while eliminating aeration, which is critical for the stability and shelf life of the final product. Every unit is designed with pharmaceutical-grade materials and smooth surfaces to facilitate rapid cleaning and validation.

Core Components of the Production Line

• Mixing and Reactor Units: Versatile vessels designed for various batch sizes, featuring thermal jackets for precise heating/cooling cycles and anchor agitators for consistent bulk mixing.
• High-Speed Homogenizers: Advanced bottom or top-entry shear tools for fine dispersion and emulsification, ensuring a uniform microscopic structure of the base.
• Vacuum Degassing Systems: Integrated vacuum modules that remove air bubbles during the mixing process, preventing oxidation and enhancing the aesthetic and chemical stability of the product.
• Filling and Dosing Integration: Seamless connectivity with downstream packaging equipment for precise dosing into aluminum or plastic tubes, jars, or sachets.

Why Partner with INEX?

• Scalable Configurations: We offer solutions for every stage of development, from compact benchtop units to massive automated industrial complexes.
• Customized Engineering: Our experts select equipment based on your specific recipe, product viscosity, required throughput, and facility constraints.
• Turnkey Integration: We manage the entire lifecycle—from design and 3D modeling to delivery, installation, staff training, and ongoing technical service.
• GMP Excellence: All designs prioritize aseptic processing and easy validation (IQ/OQ/PQ) to meet international regulatory standards.

Technical Specifications

• Product Applications: Ointments, Creams, Gels, Pastes, Emulsions.
• Vessel Volumes: From 5L (Laboratory) to 2000L+ (Industrial).
• Homogenizer Speed: Up to 3000–6000 rpm (variable frequency control).
• Vacuum Level: Down to -0.09 MPa for effective de-aeration.
• Heating Method: Electric or Steam-jacketed heating.
• Material of Construction: Product contact parts in Stainless Steel AISI 316L; outer surfaces in AISI 304.
• Control System: PLC with HMI for recipe management and batch reporting.
• Sanitation: CIP (Clean-in-Place) and WIP (Wash-in-Place) compatible designs.